X0303 4 2010-02-18 0 0000882095 GILEAD SCIENCES INC GILD 0001334682 Alton Gregg H GILEAD SCIENCES, INC. 333 LAKESIDE DRIVE FOSTER CITY CA 94404 0 1 0 0 EVP, Corp & Med Affairs Common Stock 2010-02-18 4 M 0 3000 15.265 A 21056 D Common Stock 2010-02-18 4 S 0 3000 49 D 18056 D Non-Qualified Stock Option (rght to buy) 15.2650 2010-02-18 4 M 0 3000 0 D 2014-01-28 Common Stock 3000 100000 D The options have a 5 year vesting schedule. 20% of the options vested on January 28, 2005, the first anniversary of the date of the grant. The balance vested 5% every three months thereafter until fully vested on January 28, 2009. The options expire on January 28, 2014. The exercise and sale transactions reported in this Form 4 are made pursuant to a Rule 105b-1 trading plan established by Mr. Alton on August 19, 2009. /s/ Kristen Metza by power of attorney for Gregg H. Alton 2010-02-22